3种真菌抗生素对绿僵菌和6种非目标真菌的生长影响分析

杨华,徐金柱,秦长生,揭育泽

美高梅,美高梅,美高梅,美高梅

摘要:

文章比较了两性霉素、伊曲康唑和放线菌酮对土壤内金龟子绿僵菌（Metarhizium anisopliae）、黄绿绿僵菌（M. flavoviride）和6种非目标真菌生长的影响。结果表明，伊曲康唑对毛霉(Mucor racemosus)和黑曲霉(Aspergillus niger)的抑菌效果较差，浓度达200 μg/mL时对毛霉的抑制率仅达54.84%，且对绿僵菌生长的抑制作用显著大于两性霉素和放线菌酮(P<0.01)，不适宜用于土壤绿僵菌的分离。两性霉素和放线菌酮在浓度为100 μg/mL时，对6种非目标真菌抑制率达69%以上，可作为绿僵菌分离的真菌抗生素。

关键词: 两性霉素；伊曲康唑；放线菌酮；抑菌；绿僵菌

DOI：

分类号： S763.15

基金项目：广东省林业科技创新专项（2012KJCX01601）；广东省科技计划项目(2012A020602086)。

The Influence of 3 Antifungal Agents on the Growth of Metarhizium and 6 Nontarget Fungis

YANG Hua,XU Jin-zhu,QIN Chang-sheng and JIE Yu-ze

Guangdong Academy of Forestry Science,,

Abstract:

The effects of 3 anti fungal agents on the growth of Metarhizium anisopliae， M. flavoviride strains and 6 nontarget fungis were studied. The results showed that itraconazole did not have good inhibitory effects on Mucor racemosus and Aspergillus niger, the rate of M. racemosus controlling was 54.84%,but the inhibitory effects on the growth of Metarhizium were significantly higher than that of amphotericin and cycloheximide (P<0.01), suggesting it was not suitable for Metarhizium isolation from soil. Amphotericin and cycloheximide of 100 μg/mL could inhibit over 69% of 6 nontarget fungis， and were the most suitable antifungal agents for Metarhizium isolation.

Key words: amphotericin; itraconazole; cycloheximide; inhibitory; Metarhizium

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